Biorepository to Support Research in Kidney Diseases

Yale University

Status: Invitation-only

Conditions: Kidney Diseases; Acute Kidney Injury; Acute Interstitial Nephritis

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT04343417

2000027890

R01DK128087 (U.S. NIH Grant/Contract)

1K23DK117065-01A1 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

To support advances in the understanding of pathophysiology and therapies of kidney diseases by creating a BioBank of kidney tissue, DNA, plasma, and urine from patients with kidney diseases.

Full description

A biorepository of human samples to support research to advance understanding of human kidney diseases will be created. Clinically, kidney diseases are detected by blood and urine laboratory tests. However, the underlying cause of kidney disease is often not clear on blood and urine tests. In such cases, a clinician may choose to perform a kidney biopsy to establish the diagnosis. Patients who are scheduled to undergo a kidney biopsy will be invited to participate in this proposed study.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients scheduled to undergo a clinically indicated kidney biopsy
• English or Spanish speaking

Exclusion criteria

• Under 18 years or age
• Known pregnancy
• Additional vulnerable individuals (incarcerated, institutionalized, or otherwise unable to participate in the study)
• Inability to provide informed consent

Trial design

1,000 participants in 1 patient group

Biorepository

Description:

Participants who contributed biospecimen samples (kidney tissue, blood, urine, DNA).