Bizarreness and Anomalous Self Experiences in Schizophrenia (BASES)

Toulouse University Hospital

Status: Enrolling

Conditions: Schizophrenia

Study type: Observational

Funder types: Other

Identifiers

NCT05966610

2023-A00049-36 (Other Identifier)

RC31/22/0517

Details and patient eligibility

About

Several authors suggest that the specific experience felt in clinical encounter, called Praecox Feeling, is directly linked to the psychopathology of Schizophrenia.

However, determining factors of this phenomena, whether cognitive or subjective, remains poorly studied.

Furthermore, Self-Disorders are alterations of the first-person experience regarded as specific of the disease. The investigators plan to study in an exploratory way the phenomenological and subjective links between Praecox Feeling and Self Disorders determinants, while hypothesizing that the clinician's Praecox Feeling can be positively correlated to SDs, as our main objective.

Full description

Several authors suggest that the specific experience felt in clinical encounter, called Praecox Feeling, is directly linked to the psychopathology of Schizophrenia. However, subjective, cognitive or neurophysiologic aspects of this phenomena remains poorly studied.

Furthermore, Self-Disorders (SD) are alterations of the first-person experience and of sense of agency, regarded as specific of Schizophrenia. Unlike Praecox Feeling, clinical, cognitive and neuropsychological determinants of SD are increasingly studied.

The investigators plan to study in an exploratory way the links between Praecox Feeling and SDs determinants, while hypothesizing that the clinician's Praecox Feeling can be positively correlated to SDs, as our main objective.

As a secondary outcome, the investigators will control this correlation by a comparison between SDs evaluation and clinician subjectivity.

The present study also plan to evaluate the associations between Praecox Feeling and clinical features, low and high cognitive level with attentional and social cognition evaluations.

The first step of the research project is to implement this exploratory design in a transversal multicentric setting between centers with a limited number of participants and without follow-up.

Enrollment: 12 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• People with a diagnosis of schizophrenia according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) criteria.
• Psychiatric medical situation judged clinically stable : no change of main antipsychotic in treatment in last 15 days.
• People who has given his non-opposition
• Patients affiliated to a social security system

Exclusion criteria

• Previous meeting of the participant with one of the investigators involved in the clinical assessment and scoring of the study scales.
• Person with a moderate to severe intellectual disability (clinical criteria).
• Person with a neurological pathology with cognitive impact
• Patients with legal protection