Bladder Pressure Predicting Renal Failure in Critically Ill Patients as Compared to Hemodynamic Parameters

Northwell Health

Status: Completed

Conditions: Acute Heart Failure; Acute Renal Failure

Treatments: Device: BARD® Intra-abdominal Pressure monitor

Study type: Observational

Funder types: Other

Identifiers

NCT01363505

11-021

Details and patient eligibility

About

Studies have shown that more than 30% of the overall acute decompensated heart failure (ADHF) patients develop renal dysfunction.

Several studies have tried to find a correlation between hemodynamic Parameters (blood pressure , heart rate, central venous pressure CVP) and worsening of renal function in acute decompensated heart failure patients.

Results showed that there were no correlation between baseline hemodynamics or change in hemodynamics and worsening of renal function.

Another study showed that intra-abdominal pressure (IAP) measuring was a better corollary to renal failure status then measuring cardiovascular hemodynamics using pulmonary artery catheterization in ADHF patients.. An increased IAP was associated with worse renal function and that level of IAP far below abdominal compartment syndrome may adversely affect renal function in patients with ADHF.

Enrollment: 16 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Any ICU(intensive care unit) or CCU(critical care unit) patient older than 18 y.
• Patient diagnosed on admission with pulmonary edema/CHF (fluid in the lungs) - independently from the baseline renal function.
• No subject will be accepted to take part in the study unless they are able to sign or if Health care proxy signs a consent

Exclusion criteria

• Pregnant women
• Cognitively impaired patients
• Age<18 yrs old
• Patients diagnosed on admission with ARDS.
• Patients admitted with a diagnosis of sepsis ( WBC> 12000, CXR findings consistent with pneumonia, positive blood cultures on admission, UTI)

Trial design

16 participants in 1 patient group

Acute CHF patients

Description:

Acute CHF patients with BARD Intra-abdominal pressure monitors in ICU

Treatment:

Device: BARD® Intra-abdominal Pressure monitor