Bladder Wall Blood Perfusion Pattern and Sexual Dysfunction in Female Patients With Lower Urinary Tract Symptoms, and the Association of That Perfusion Pattern and Therapeutic Efficacy of Antimuscarincs for Female Overactive Bladder Syndrome.

Far Eastern Memorial Hospital

Status: Completed

Conditions: Lower Urinary Tract Symptoms

Treatments: Drug: Tolterodine SR

Study type: Interventional

Funder types: Other

Identifiers

NCT01282840

099049-F

Details and patient eligibility

About

Overactive bladder syndrome (OAB) affects around 17 % of female population. However, the etiology of OAB is complicated and unclear in many aspects. Bladder wall thickness had been reported to be strongly associated with OAB, but its use as a screening tool remains controversial. Besides, few studies reported patterns of sexual dysfunction in female patients with lower urinary tract symptoms (LUTS). Therefore the aims of our study were to analyze the bladder wall blood perfusion pattern in female LUTS patients, the association of between the bladder wall blood perfusion pattern and the efficacy of anti-muscarinic treatment for female OAB, and the patterns of sexual dysfunction in the female LUTS patients.

Enrollment: 676 patients

Sex: Female

Ages: 20 to 99 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• all cases are female patients with lower urinary tract symptoms

Exclusion criteria

• nil

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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676 participants in 1 patient group

Bladder wall blood perfusion pattern

Other group

Treatment:

Drug: Tolterodine SR