Bleeding in Critically Ill Children With Underlying Oncologic Diagnoses

Memorial Sloan Kettering Cancer Center (MSK)

Status: Completed

Conditions: Cancer; Bleeding

Study type: Observational

Funder types: Other

Identifiers

NCT04170231

19-407

Details and patient eligibility

About

"Bleeding in Critically Ill Children with Underlying Oncologic Diagnoses ," will be a prospective observational cohort study looking at the epidemiology of bleeding in the pediatric ICU population at MSK.

Enrollment: 93 patients

Sex: All

Ages: 28 days to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All children (≥28 days old through 18 years of age) with an oncologic diagnosis admitted to the PICU at Memorial Sloan Kettering Cancer Center
• An oncologic diagnosis will include those with a cancer diagnosis or those being treated at MSK for blood disorders, immunodeficiencies and complications of transplant.

Exclusion criteria

• Preterm infants (<44 weeks gestation at age of enrollment) as in these patients most bleeding etiologies are specific to the neonatal period and the bleeding assessment tool is not calibrated for this population
• Known limitation of care at enrollment (standing Do Not Resuscitate order), as the interventions and clinical outcome would be biased
• Pre-existing bleeding disorders