Blood and Tissue Sample Collection for Future Colon Cancer Biomarker Studies in Patients Undergoing Colonoscopy

Vanderbilt University

Status: Completed

Conditions: Health Status Unknown; Colorectal Cancer

Treatments: Other: biologic sample preservation procedure; Procedure: diagnostic colonoscopy

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT00897403

CDR0000546530

P30CA068485 (U.S. NIH Grant/Contract)

VU-VICC-IRB-061096

VU-VICC-GI-0661

Details and patient eligibility

About

RATIONALE: Collecting and storing samples of blood and tissue from patients undergoing colonoscopy to study in the laboratory may help doctors learn more about colon cancer and identify biomarkers related to colon cancer in the future.

PURPOSE: This laboratory study is collecting blood and tissue samples for future colon cancer biomarker studies in patients undergoing colonoscopy.

Full description

OBJECTIVES:

• Collect blood and tissue samples (including polyps, abnormal growths, cancer, and normal tissue) from patients undergoing colonoscopy.

OUTLINE: Patients undergo blood and tissue sample collection during colonoscopy. Samples are stored for future biomarker proteomic profiling.

Enrollment: 6,446 patients

Sex: All

Ages: 25 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

DISEASE CHARACTERISTICS:

• Scheduled for colonoscopy as routine screening or for a specific problem

PATIENT CHARACTERISTICS:

• Not pregnant

PRIOR CONCURRENT THERAPY:

• No concurrent participation in a clinical trial to treat cancer or prevent cancer recurrence