Blood Components Changes by Using of Ringer's Lactated as Detergent In Autologous Blood Cell Transfusion

Maternal and Child Health Hospital of Foshan

Status: Withdrawn

Conditions: Placenta Accreta Spectrum

Treatments: Other: Ringer's Lactated

Study type: Interventional

Funder types: Other

Identifiers

NCT04927988

MCHHFoshan-2101

Details and patient eligibility

About

Placenta accreta spectrum (PAS) disorders are associated with increased maternal morbidity and mortality related to life-threatening hemorrhage, and greater potential need for blood transfusion. Clinical evidences have confirmed that the use of autologous blood cell transfusion is safe and effective for patients with obstetric haemorrhage. Normal saline is the solution recommended for red cell washing, administration and salvage. However, there is growing concern that normal saline is more toxic than balanced, buffered crystalloids such as Lactated Ringer's and Plasma-Lyte. The purpose of this study is to evaluate the blood components using of Ringer's Lactated by a prospective, single-center, open, and single-arm clinical trial.

Sex: Female

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Between 18 and 45 years old
• Without health problem nor disease requiring regular medical treatment

Exclusion criteria

• subject with contraindication for drawing blood
• Subject with physical or mental disability or restriction of liberty that would prevent autotransfusion

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 1 patient group

Arm 1.

Other group

Description:

Using of Ringer's Lactated

Treatment:

Other: Ringer's Lactated