Blood Flow Change After Free Flap Surgery in Diabetic Patients

Asan Medical Center

Status: Completed

Conditions: Diabetes

Treatments: Drug: Alprostadil

Study type: Observational

Funder types: Other

Identifiers

NCT03027219

S2016-2043-0003

Details and patient eligibility

About

We aim to evaluate the flow change of arterial anastomosis site during free flap surgery in diabetic patients.

Full description

Objective: flow change of arterial anastomosis site during free flap surgery in diabetic patients.

Background: No research was published about flow change of arterial anastomosis site of the free flap during surgery.

Plan: Using Duplex sonography, various parameters related flap perfusion will be evaluated before and after the administration of alprostadil.

Enrollment: 44 patients

Sex: All

Ages: 18 to 79 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Plan to receive free flap transfer under general anesthesia
2. Age: >=18 and <80 years old
3. History of diabetes mellitus
4. Administration of alprostadil during surgery
5. Volunteer, who are provided written informed consent prior to study participation

Exclusion criteria

1. Refuse the participation of study
2. >= American society of anesthesiologist physical status IV
3. Use of any vasopressor or inotropic for hemodynamic instability before participation of study
4. Inappropriate subjects who are identified by researchers