Blood Flow Restriction and Functionality in Older Adults

Concordia University, Montreal

Status

Invitation-only

Conditions

Older Adults (65 Years and Older)

Blood Flow Restriction and Low-Intensity Resistance Training

Blood Flow Restriction (BFR) Training Effects

Older Adults At Risk of Falling

Treatments

Other: Blood flow restrictions in combination with low-intensity resistance training

Study type

Interventional

Funder types

Other

Identifiers

NCT06724393

30018588

Details and patient eligibility

About

Resistance training is beneficial for stimulating muscle and bone growth and is uniquely important for older adults to avoid frailty and to maintain bone density. Seniors tend to be anxious to use a large resistance or try heavier weights as it is not common for them to exercise this way. Therefore, blood flow restriction is a fantastic way to increase intensity while keeping the resistance low. Wearing blood flow restriction straps allows the muscles to adapt to working at a lower oxygen pressure, therefore, mimicking a higher intensity. Additionally, as we age, oxygen consumption decreases, commonly due to loss of lean body mass and a reduced maximum heart rate. However, resistance training can counteract these declines by reducing the resting heart rate and improving cardiac output, therefore, bettering oxygen consumption.

The study will consist of 10 weeks of resistance exercises performed twice per week. The classes will be open to seniors of 60 years of age or older. The classes will be held on zoom- allowing for easy access, no travel and an opportunity for seniors to be active in their own home. The exercises will consist of general resistance training movements focusing all the major muscle groups. One group of seniors will wear blood flow restriction bands on both legs at the upper thigh and a control group which will complete the same exercise classes with no restriction.

Before, at midpoint and after the 10 weeks, the participants will perform strength tests using the BIODEX and three functional tests focusing on the lower extremity. There will be a practice trial for all the functional tests where results are not recorded. Once the practice is completed, the participants will have one trial of each test. The BIODEX is a dynamometer that allows testing in many different settings including rehabilitation. During the functional tests, the participants will be asked to wear a VO2 non-invasive mask (VO2 Master) to measure their oxygen consumption. The functional tests will include:

Sit to stand: rise from a chair as many times as possible without using hands or arm rests to help.
Timed up a go: Rise from a chair and walk 8ft as fast as possible without running and return to sit on the chair.
Sitting-rising test: lowering to the floor and coming back up without using hands, knees or arms.

Thus, the purpose of this study is three-fold: 1) To assess the effects of the 10-week online exercise intervention on strength and functionality 2) To assess the effects of the 10-week intervention on oxygen consumption using a VO2 non-invasive mask and 3) To assess if the addition of blood flow restriction over a 10-week intervention increases the improvements in strength and oxygen consumption compared to the control group.

Enrollment

30 estimated patients

Sex

All

Ages

60+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Participants will be both male and female, aged 60 years or older. They must be willing to participate in two exercise sessions per week for 10 weeks held online. Participants must also be able to visit Loyola campus for pre-, mid- and post-intervention testing.

Exclusion criteria

Exclusion criteria include chronic disease (with the exclusion of hypertension), use of steroidal drugs, blood clot or varicose veins, part-take in excessive physical activity (over 3-4 hours a week of moderate to high intensity training) and have scheduled vacation or absence in the ten-week period. The reason behind excluding seniors who part-take in excessive physical activity is because the classes will be low intensity. Due to the fact that participants will be healthy older adults without chronic conditions, a medical form from a physician will not be necessary.