Blood Flow Restriction Resistance Exercise and Cardiac Cycle Dynamics

Montclair State University

Status

Not yet enrolling

Conditions

Cardiac

Treatments

Other: Blood flow restriction resistance exercise

Study type

Interventional

Funder types

Other

Identifiers

NCT07344740

IRB-FY25-26-5034

Details and patient eligibility

About

Blood flow restriction resistance exercise uses partial vascular occlusion of a limb during low weight resistance exercises to stimulate muscle strengthening and growth. This is commonly used during rehabilitation from an injury. Because blood flow in and out of the limbs is decreased, this may have consequences for blood flow through the heart. The purpose of this study will be to test cardiac dynamics during blood flow restriction resistance exercise to determine if cardiac blood flow is impacted. It is hypothesized that both non-BFR exercise and BFR exercise will increase heart rate shortening various cardiac cycle parameters, but BFR exercise will increase the isovolumetric contraction time vs non-BFR exercise due to an increase in total peripheral resistance. It is also hypothesized that BFR exercise will lower early ventricular filling parameters due to lower venous return.

Enrollment

40 estimated patients

Sex

All

Ages

18 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Generally healthy

Exclusion criteria

Uncontrolled hypertension
Peripheral vascular disease
Lymphedema
Sickle cell anemia
Heart failure
Stroke history
Heart attack history
Rheumatoid arthritis
Chronic kidney disease
Diabetes
Severe neuropathy
Any condition that may make blood flow restriction resistance exercise riskier like history of blood clots
Use of coagulant therapy
Susceptible to blood clots
Obesity