Effect of Blood Flow Restriction Training Exercises on Hand Grip Strength in Hemiparetic Cerebral Palsied Children

Cairo University (CU)

Status: Begins enrollment this month

Conditions: Cerebral Palsy Spastic Hemiplegic

Treatments: Behavioral: control group; Device: Blood Flow Restriction Training Exercises group

Study type: Interventional

Funder types: Other

Identifiers

NCT07347795

P.T.REC/012/005952

Details and patient eligibility

About

The study aims to investigate the effect of blood flow restriction (BFR) training exercises on the hand grip strength of children with hemiparetic cerebral palsy. Hand grip strength is a vital component of motor function and is often severely compromised in children with hemiparetic CP, which can significantly impact their daily activities and quality of life. Blood flow restriction (BFR) training is a novel exercise technique where a cuff or band is used to partially occlude blood flow during low-intensity resistance exercises. This method has been shown to stimulate muscle growth and strength gains similar to those achieved through high-intensity strength training, without the need for high loads. Given the unique physiological challenges faced by children with hemiparetic CP, BFR training could provide an effective alternative to traditional strength training methods.

Enrollment: 40 estimated patients

Sex: All

Ages: 6 to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Age will range from 6-12 years

• Diagnosed with hemiparetic cerebral palsy (right or left side).
• According to Modified Ashwer scale, has grade 1 or 1+ grade
• Children with the ability to understand and follow verbal commands and instructions used during training and tests

Exclusion criteria

• Any contraindications to exercise, such as moderate or severe spasticity, orthopedic deformities, or other serious health conditions.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Control group

Active Comparator group

Description:

The control group performs traditional hand grip strengthening exercises, focusing on similar exercises but without blood flow restriction. Both groups participate in a similar frequency and duration of training, with a gradual increase in repetitions over the 8 weeks

Treatment:

Behavioral: control group

Study group

Experimental group

Treatment:

Device: Blood Flow Restriction Training Exercises group