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Blood Flow Within Active Myofascial Trigger Points Following Massage

University of Colorado Denver (CU Denver) logo

University of Colorado Denver (CU Denver)

Status

Completed

Conditions

Myofascial Pain
Tension-type Headache

Treatments

Other: Trigger point release
Other: Ultrasound

Study type

Interventional

Funder types

Other

Identifiers

NCT02389140
14-1582
UL1TR001082 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The physiological response at the myofascial trigger point (MTrP) to massage is not known, yet would provide important objective evidence for a treatment effect and clarify the resolution process of a MTrP.

Full description

The physiological response at the myofascial trigger point (MTrP) to massage is not known, yet would provide important objective evidence for a treatment effect and clarify the resolution process of a MTrP. The long-term goal is to understand how therapeutic intervention affects the physiology of the MTrP. The objective of the proposed research is to assess, in a placebo controlled trial, the effectiveness of trigger point release massage (also known as ischemic compression) on blood flow at an active MTrP. The central hypothesis is that the contraction nodule of an active MTrP is characterized by an ischemic state comprised of reduced blood flow and subsequent dysregulation in carbohydrate metabolism. The investigators hypothesize that trigger point release (TPR) can positively impact blood flow leading to a change in high energy carbohydrate tension. The present study has been formulated, in part, from a preliminary study conducted by the investigators, which supports reduced blood flow and physiological disruption at active MTrPs. The proposed research will provide a physiological basis for massage to corroborate subjective reports of reduced pain sensitivity, impart credibility to treatment techniques, and provide insight into a mechanism of action for healing the MTrP.

Enrollment

28 patients

Sex

All

Ages

21 to 49 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Chronic or episodic tension-type headache
  • active MTrP in upper trapezius
  • age 21-49
  • BMI between 18.5-24.9
  • either gender
  • any race or ethnicity

Exclusion criteria

  • No or latent MTrP in the upper trapezius
  • migraine 4+/month
  • cluster headache
  • fibromyalgia
  • neurological disease (e.g. Alzheimer's disease, Parkinson's disease, muscular dystrophy, multiple sclerosis)
  • cardiovascular disease (e.g. prior heart attack or stroke)
  • diabetes
  • pregnancy
  • a bleeding disorder (Self-report of hemophilia, known lack/deficiency of clotting factors, or presently °taking anti-coagulants (e.g. warfarin, Coumadin))
  • narcotic use
  • currently receiving massage
  • prior trigger point injection or needling therapies
  • allergy to lidocaine-type anesthetics such as lidocaine and prilocaine

Trial design

Primary purpose

Other

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

28 participants in 2 patient groups

Trigger point treatment
Experimental group
Description:
Trigger point release
Treatment:
Other: Trigger point release
Ultrasound
Sham Comparator group
Description:
Sham US at Trigger point
Treatment:
Other: Ultrasound

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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