Blood Mercury Levels Following Retrograde Amalgam Surgeries

Masoud Saatchi

Status and phase: Completed; Phase 4

Conditions: Blood Mercury Concentration

Treatments: Procedure: Amalgam

Study type: Interventional

Funder types: Other

Identifiers

NCT01428609

MUI79275

Details and patient eligibility

About

The aim of this study is to determine the blood's mercury level of patients who had amalgam root end filling surgeries. It is to be examined if the mercury concentration in blood is elevated by using amalgam retroseal.

Full description

• A total of 14 patients who needs surgical root canal therapy (SRCT) participated in this clinical study.
• The Isfahan University Human Subjects Review Committee approved the protocol of the study.
• All patients filled in the consent form.
• Apicoectomy with retrograde amalgam filling performed for all participant.
• Blood samples were collected in three period of time immediately before and immediately after each surgery and also one week later.
• Each time 10 ml blood was drawn from each patient.
• Analysis of total mercury in blood samples was performed using cold-vapor atomic absorption spectrometry

Enrollment: 14 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• older than 18 years
• without physician-diagnosed psychological, behavioral, neurological, immunosuppressive, or renal disorders
• having a tooth that required apical surgery

Exclusion criteria

• using tobacco and alcohol one week before surgery and during the study
• dealing with mercury in their job like dentists, stonemason, mine workers