Blood Pressure and Cardiac Autonomic Adaptations to Isometric Exercise Training

Canterbury Christ Church University

Status: Completed

Conditions: Hypertension

Treatments: Other: Isometric exercise training

Study type: Interventional

Funder types: Other

Identifiers

NCT05025202

18/SAS/47C

Details and patient eligibility

About

A randomized, sham-controlled intervention measuring the effects of isometric exercise training (IET) on blood pressure and cardiac autonomics.

IET has been proven effective in a plethora of randomized trials, but very little research has employed a sham-controlled design. This researched involved the recruitment of 30 participants who completed a 4 week IET intervention, sham control of the IET intervention, or a non-intervention control period. Pre and post blood pressure and cardiac autonomic measures were acquired and analysed.

The hypothesis of this trial was a significant effect of IET on blood pressure, with no such effects following the sham control or normal control interventions.

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy with no significant health conditions contraindicating exercise
• Over 18 years of age
• Physically inactive

Exclusion criteria

• Achieving current physical activity guidelines
• Abnormal resting ECG
• under 18

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 3 patient groups

IET

Experimental group

Description:

Participants allocated to this arm performed 4 weeks of isometric wall squat exercise training, 3 times per week.

Treatment:

Other: Isometric exercise training

Sham

Sham Comparator group

Description:

Participants allocated to this arm performed 4 weeks of isometric wall squat training, but the training prescription was intentionally provided at an insufficient intensity to achieve any physiology stimulus.

Treatment:

Other: Isometric exercise training

No intervention control

No Intervention group

Description:

Participants allocated to this arm did not perform any exercise and were required to maintain usual daily habits.