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Blood Sample Collection for Experimental Blood Test to Track Liver Cancer

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Thomas Jefferson University

Status

Completed

Conditions

Hepatocellular Carcinoma

Study type

Observational

Funder types

Other

Identifiers

NCT04720430
19D.737
JT 13572 (Other Identifier)

Details and patient eligibility

About

This study investigates if an experimental blood test can help predict how well cancer will remain under control with treatment. Ther experimental blood test involves measuring mircoRNAs. MicroRNAs are small molecules which help regulate how genes are expressed. This information may help researchers guide treatment for other patients in the future.

Enrollment

7 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Provide signed and dated informed consent form
  • Willing to comply with all study procedures and be available for the duration of the study
  • Definite diagnosis of hepatocellular carcinoma established (by standard radiographic or histologic criteria)
  • Felt to be reasonable candidate for liver transplantation, potentially contingent on success of down-staging therapy

Exclusion criteria

  • Either active or recent solid organ cancer other than hepatocellur carcinoma (HCC) within the last 5 years, unless determined by transplant hepatology team not to represent contra-indication to liver transplantation
  • Contra-indication to LRT (as assessed by interventional radiologist, for example severe thrombocytopenia, severe vascular disease precluding access, etc)
  • History of prior liver transplantation
  • Active or prior systemic therapy for HCC

Trial contacts and locations

1

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Central trial contact

Jesse Civan, MD

Data sourced from clinicaltrials.gov

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