Blood Sampling of Healthy Volunteers for Immunological Research

Netherlands Cancer Institute (NKI)

Status: Enrolling

Conditions: Healthy Volunteers

Treatments: Other: Blood sample

Study type: Interventional

Funder types: Other

Identifiers

NCT03819829

B18HIR

Details and patient eligibility

About

This protocol will be used to collect crucial components of the immune system from healthy volunteers for the characterization of immune cells in fresh blood. A pipeline has been set up for comprehensive immune phenotyping of both lymphoid and myeloid cells within 24 hours after blood withdrawal.

Full description

In order to properly compare the immunobiology of healthy volunteers to (advanced) cancer patients, the investigators use age-matched controls with no history of cancer and no potentially interfering medication.

Healthy volunteers will be asked to donate 5 tubes of blood

Enrollment: 50 estimated patients

Sex: All

Ages: 36+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age above 35 years
• Written informed consent
• No history of cancer
• No use of systemic immunosuppressive medication (eg. corticosteroids). Local use of corticosteroids (eg. topical or inhalation) is allowed.

Exclusion criteria

• Fever 14 days before blood withdrawal
• Donated blood for the same program within the last 2 years
• Pregnancy

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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50 participants in 1 patient group

Blood sample

Other group

Description:

Blood sample

Treatment:

Other: Blood sample