Blood Transfusion Among Patients With Pelvic Fracture in China (PBM)

Central South University

Status: Unknown

Conditions: Blood Transfusion Complication; Transfusion Reaction; Pelvic Fracture

Study type: Observational

Funder types: Other

Identifiers

NCT03855644

SXKThirdXiangyaHCSU

Details and patient eligibility

About

According to the patient's blood management concept, this study intends to collect basic information, surgical data, blood transfusion related data and patient prognosis data of patients with pelvic fractures, and to construct a predictive model of intraoperative blood transfusion in patients with pelvic fractures by multiple linear regression analysis. To guide physicians use blood accurately during surgery. Prompt doctors to reduce blood transfusion dose and improve patient prognosis by stopping bleeding and blood recovery before surgery.

Full description

2.1 Research Objectives: This study aims to construct a blood transfusion model for pelvic fractures, to guide the rational use of blood during surgery, and to improve the prognosis of patients.

2.2 Research content: 2.2.1 Collect basic data, surgical data, blood transfusion related data and patient prognosis related data of patients with pelvic fractures.

2.2.2 Gradually incorporate and exclude data from multiple linear regression models.

2.2.3 Verify the specificity and sensitivity of the intraoperative blood transfusion prediction model.

2.2.4 Create a visualization window to guide clinical blood. 2.2.5 Put into clinical trial and feedback, and continue to verify 2.3 Key issues to be resolved 2.3.1 The factors related to intraoperative blood transfusion in patients with pelvic fractures (such as blood oxygenation, blood loss, HB value, intraoperative autologous blood recovery, blood pressure, heart rate, etc.) were initially screened by univariate analysis.

2.3.2 Reasonably standardize the objective and subjective indicators of different units and different institutions.

2.4 Expected research results Intraoperative blood transfusion prediction model and window for patients with pelvic fractures.

2.5 Assessment indicators Published 1-2 papers. Create a visual applet and put it into trial.

Enrollment: 2,000 estimated patients

Sex: All

Ages: 1 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• (1) 1<Age<80, and Chinese residents living in China more than 3 years;
• (2) Hemoglobin value less than 100g/L during hospitalization;

Exclusion criteria

• (1) Participants who suffered from pelvic fracture within 3 months
• (2) Participants who suffer from pathological fractures of the pelvis caused by malignant tumors
• (3) Participants with chronic anemia and coagulopathy
• (4) Participants who rufuse blood transfusion

Trial design

2,000 participants in 1 patient group

Pelvic fracture patients

Description:

(1) 1\<Age\<80, and Chinese residents living in China more than 3 years; (2) Hemoglobin value less than 100g/L during hospitalization; Not suffered from pelvic fracture within 3 months; Not suffer from pathological fractures of the pelvis caused by malignant tumors; without chronic anemia and coagulopathy; accept blood transfusion