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Blood Transfusions in Thalassemia Patients, Complications and Adverse Effects

H

HaEmek Medical Center, Israel

Status

Completed

Conditions

Thalassemia
Sickle Cell Anemia

Treatments

Other: Clinical medical record summary

Study type

Observational

Funder types

Other

Identifiers

NCT00971880
0039-09-EMC

Details and patient eligibility

About

Patients suffering from Thalassemia or another hemoglobinopathies required regular blood transfusions. The complications and adverse effects of blood transfusions can be classified as immediate and late. Among the immediate effects the most common are allergic reactions and fever, besides congestive heart failure in patients with cardiomyopathy. The late effects are mostly related to blood transmitted infections like HIV or Hepatitis C infections.

The purpose of this study is to summarize the data of those complications in a cohort of 100 patients receiving regular blood transfusion.

Full description

About 100 patients aged several months to 50 years are treated in the Pediatric Hematology Unit, most of those patients receive blood transfusions monthly. The adverse reactions were routinely recorded during each transfusion. All the patients were also screened annually for the incidence of blood transmitted infections principally HIV and Hepatitis C. All those records will be systematically screened and all the immediate or late adverse reactions and complications related to blood transfusions will be summarized.

A second goal of this study will be to control the staff strictness related to the ministry of health protocol dealing to blood transfusions.

Enrollment

100 estimated patients

Sex

All

Ages

1 month to 50 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients receiving blood transfusions due to chronic hematologic disorders

Exclusion criteria

  • Not applicable

Trial design

100 participants in 1 patient group

Patients receiving blood transfusions
Description:
All the patients with blood disorders that require blood transfusions
Treatment:
Other: Clinical medical record summary

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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