Blue Diode Laser Vaporization for BPH

The Chinese University of Hong Kong

Status: Enrolling

Conditions: BPH

Treatments: Device: Blue diode laser

Study type: Interventional

Funder types: Other

Identifiers

NCT07115147

CRE2025.162

Details and patient eligibility

About

This is a prospective data collection of subjects using blude diode laser for the treatment of BPH.

Full description

This is a prospective single-arm study evaluating the outcome of blue diode laser vaporization. The energy from a 450nm blue laser vaporization will be used for the treatment of BPH. The study period for each patient is 1 year. Recruited subjects will then be followed up at 3 months, 6 months and 12 months after operation. Blood tests, urine tests, ultrasound for prostate volume assessment, uroflowmetry and the same set of questionnaires will be performed again during follow-up for assessing the clinical progress. Any adverse event and unplanned admission will also be documented.

Enrollment: 10 estimated patients

Sex: Male

Ages: 50+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male ≥ 50 years
• Symptomatic BPH

Exclusion criteria

• Additional procedure is needed e.g. cystolithotripsy, orchidectomy etc2. Known Ca prostate patients
• Patients with history of TURP
• Known Urethral stricture / Bladder stone / Hypercontractile bladder
• Known neurological diseases which may affect bladder function (e.g. Parkinsonism, stroke) 6. Contraindicated to undergo TURP (e.g. not fit for GA/SA, active urinary tract infection, fail to be placed in lithotomy position, uncorrectable coagulopathy, antiplatelet or anticoagulant which cannot be stopped)

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 1 patient group

Blue light laser Arm

Experimental group

Description:

450nm center wavelength blue diode 200W laser is employed for the surgical procedure

Treatment:

Device: Blue diode laser