Blueberry Consumption and Type 2 Diabetes

Albany Research Institute, Inc.

Status

Completed

Conditions

Type2 Diabetes

Treatments

Other: Placebo

Other: Blueberry

Study type

Interventional

Funder types

Other

Identifiers

NCT02972996

HNS 01

Details and patient eligibility

About

Lifestyle strategies that include dietary modification, such as consumption of a plant-based diet, are well recognized in disease prevention and may improve type 2 diabetes. Various components of a plant-based diet may contribute to its beneficial health effects, but there has been keen interest in the possibility that plant polyphenols may have a role. Blueberries are dietary sources of polyphenols, specifically anthocyanins. To date there are few human clinical trials evaluating the beneficial health effects of blueberries in populations with type 2 diabetes. The objective of the study is to determine if freeze-dried blueberries compared to a blueberry placebo will improve cardiometabolic parameters in men with type 2 diabetes.

Enrollment

55 patients

Sex

Male

Ages

45 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Male
Ages 45 to 75 years at beginning of study
BMI >25 kg/m2
HbA1C > 6.5 and < 9
Medical diagnosis of type 2 diabetes for at least 6 months

Exclusion criteria

Use of insulin
Presence of chronic kidney disease (GFR < 45 mL/min), liver cirrhosis, gastrointestinal disease, pancreatic disease, or malabsorption syndromes
Weight loss of >10% of body weight over the last 6 months; routine participation in heavy exercise
Heavy smokers (>20 cigarettes per day)
Unable or unwilling to give informed consent or communicate with study staff
Other medical, psychiatric, or behavioral factors that in the judgment of the Principal Investigators may interfere with study participation or the ability to follow the intervention protocol
Allergies to blueberries or blueberry products