BMAC Loaded Collagen Jumping the Gap Around Immediate Implants

Cairo University (CU)

Status: Enrolling

Conditions: Implant Site Reaction; Dental Implantation

Treatments: Drug: BMAC/ collagen; Procedure: Autograft harvesting from chin

Study type: Interventional

Funder types: Other

Identifiers

NCT05817526

BMAC around immediate implants

Details and patient eligibility

About

The present study aims to evaluate the effect of utilization of BMAC/ collagen on marginal bone changes around immediate implants in the esthetic zone of maxilla.

Methodology: Twenty dental implants will be installed in the esthetic zone and patients will be randomly divided into two groups:

study group: The jumping gap surrounding the immediate implants will be grafted with BMAC/collagen, whereas in the control group, autograft from the chin will be used to fill the defect. Cone beam CT (CBCT) will be requested Preoperative, immediate and 4 months Postoperative for assessment of marginal bone changes around implants.

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Full description

The aim of present study is to evaluate the effect of utilization of bone marrow aspirate concentrate (BMAC) loaded on collagen on the marginal bone changes around immediate implants in the esthetic zone of maxilla.

Methodology: Twenty dental implants will be installed in patients suffering from non- restorable teeth in esthetic zone.

Patients will be randomly divided into two equal groups:

study group: The jumping gap surrounding the immediate implants will be grafted with bone marrow aspirate concentrate loaded on collagen, whereas in the control group, autogenous bone graft from the chin will be used to fill the peri-implant defect. CBCT will be requested Preoperative, immediate and 4 months Postoperative for assessment of marginal bone changes around dental implants.

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Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with non- restorable teeth in esthetic zone
• Patients above 18 us
• Highly motivated patients.

Exclusion criteria

• patients with systemic diseases • immunocompromised patients . Patients with bleeding disorders

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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20 participants in 2 patient groups

BMAC/ collagen

Active Comparator group

Description:

Bone marrow aspirate concentrate loaded on collagen utilization for filling peri-implant gap around immediate dental implants in the Maxillary esthetic zone

Treatment:

Drug: BMAC/ collagen

Autograft

Active Comparator group

Description:

Autograft harvested from chin utilization for filling peri-implant gap around immediate dental implants in the Maxillary esthetic zone

Treatment:

Procedure: Autograft harvesting from chin