BMI and Lymph Node Count in Colorectal Cancer

Klinikum Floridsdorf

Status: Completed

Conditions: The Aim of This Study is to Determine the Influence of BMI and Lymph Node Status on OS in CRC Patients in the Long Term

Treatments: Other: no intervention, retrospective data analysis

Study type: Observational

Funder types: Other; NETWORK

Identifiers

NCT06334926

EK 18-002-VK

Details and patient eligibility

About

Background and aim: Colorectal Cancer (CRC) is one of the most frequent cancer entities in the western world. It is known that obesity is one of the major risk factors for CRC. In contrast, mild obesity seems to have a positive effect on postoperative outcome, which is known as the "obesity paradox". Also, the number of resected lymph nodes (LN) during surgery is very important for correct staging. The aim of the present project is to evaluate the impact of BMI and LN-yield on long term overall survival (OS) of CRC patients treated with curative intent.

Methods: Patients treated for CRC between 1998 and 2011 at the Klinik Favoriten in Vienna, Austria were analyzed in this retrospective single-center cohort analysis concerning OS.

Enrollment: 1,192 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• colorectal carcinoma
• treated at the Klinik Favoriten between 1998 and 2011
• elective or acute surgical setting
• curative intent
• older than 18 years

Exclusion criteria

• other carcinoma (anal, metastases, ...)
• treated before 1998 or after 2011
• palliative intent
• younger than 18 years

Trial design

1,192 participants in 2 patient groups

Colon cancer patients

Description:

Retrospective data analysis of the subgroup of patients suffering from colon carcinoma

Treatment:

Other: no intervention, retrospective data analysis

Rectal cancer patients

Description:

Retrospective data analysis of the subgroup of patients suffering from rectal carcinoma

Treatment:

Other: no intervention, retrospective data analysis