Body Composition Analysis in Cirrhotic Undergoing Paracentesis

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

Status: Unknown

Conditions: Liver Cirrhosis; Ascites

Treatments: Behavioral: Body composition in paracentesis

Study type: Observational

Funder types: Other

Identifiers

NCT02022150

GAS-819-12/13-1

Details and patient eligibility

About

Ascites is a frequent complication of liver cirrhosis, initial treatment consists on diuretics intake, however, as the disease progresses this complication becomes more severe, consequently other therapeutic options are used.

Paracentesis is indicated when severe ascites is present and it should be accompanied by albumin infusion.

Nutritional status is generally affected in patients with liver cirrhosis, even more patients with severe ascites show decreased energy intake due to gastric compression.

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Any genre.
• Age 18-70 years old.
• Diagnosis of liver cirrhosis of any etiology (documented by clinical, biochemical, radiological and / or biopsy.
• Presence of high volume ascites
• The signing of informed consent will be required for the inclusion of any patient.

Exclusion criteria

• Hepatic encephalopathy grade III or IV. 2) liver transplantation.
• Congestive heart failure.
• Hemodialysis.
• Acute or chronic renal failure.
• Nephrotic syndrome with protein loss.
• Alcoholism active in the last 6 months.
• Pregnancy.
• upper gastrointestinal bleeding.

Trial design

20 participants in 1 patient group

Body composition in paracentesis

Description:

Taking blood samples and bioelectrical impedance, Psychometric Hepatic Encephalopathy Score (PHES) and Critical Flicker Frequency (CFF) before and after paracentesis.

Treatment:

Behavioral: Body composition in paracentesis