Body Composition in Older Adults (BODI)

Royal Marsden NHS Foundation Trust

Status: Not yet enrolling

Conditions: Nutrition; Older Adults; Sarcopenia in Elderly; Body Composition Changes; Cachexia; Cancer; Sarcopenia

Treatments: Other: No Intervention: Observational Cohort

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT06630754

CCR6064

Details and patient eligibility

About

The primary aim of the study is to explore body composition in older adults (aged 70 years and over) with cancer, undergoing systemic anticancer treatment. Additional aims include to explore the extent of body composition changes and whether changes are tumour specific, the incidence for cancer-related cachexia and sarcopenia and finally, how body composition can inform nutritional management of older adults with cancer.

To do this, the investigators applied for and were awarded funding from a company called Nutricia to pay for a band 4 (0.6 WTE for 7 months) to take monthly body composition measures on the patients who are eligible, accepting of assessment by the Senior Adult Oncology Programme (SAOP) and consent to these measures. Measurements will include an analysis from the Bioelectrical Impedance Analysis (BIA) machine which will quantify fat, lean muscle, and water content; waist to hip ratio; handgrip strength; calf circumferences. Socio-demographic data will also be collected.

Descriptive data analysis will take place to explore possible trends and associations which may inform future research and drive even further personalised care for this growing and typically underrepresented in research, population.

Enrollment: 30 estimated patients

Sex: All

Ages: 70+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults eligible and accepting of assessment in the SAOP.

  1. adults aged 70 years and over
  2. a cancer diagnosis
  3. just starting SACT
  4. able to provide at least 2 data sets during the study period (baseline + at least 1 research clinic visit)
  5. willing and able to provide written informed consent

Exclusion criteria

• No further exclusions

Trial design

30 participants in 1 patient group

adults aged 70yrs and older, eligible, and accepting of assessment in the SAOP.

Treatment:

Other: No Intervention: Observational Cohort