Body Weight Growth After Birth and Bronchopulmonary Dysplasia

Army Medical University of People's Liberation Army

Status: Withdrawn

Conditions: Preterm; Bronchopulmonary Dysplasia

Treatments: Other: poor body weight growth; Other: good body weight growth

Study type: Observational

Funder types: Other

Identifiers

NCT05053269

2020228

Details and patient eligibility

About

Bronchopulmonary dysplasia (BPD) is one of the most common, complex, and severe diseases in preterm infants. BPD was first described as chronic pulmonary disease in survivors of severe respiratory distress syndrome (RDS) in 1967, which was also called as the "old" BPD. In recent years, the definition for BPD has developed a lot. The National Institute of Child Health and Human Development (NICHD) workshop in 2018 assessed BPD at 36 post-menstrual age (PMA) along with radiographic confirmation and used a severity grading of I-III. Although with effective surfactant supplement and oxygen support, BPD brings a great challenge to neonatologists.

Full description

Besides persistent inflammation, prolonged invasive ventilation and oxidative damage. body weight is the one of the most important factors to induce BPD. Poor extrauterine growth is commonly described in extremely preterm infants. But, the relationship of postnatal growth with BPD and respiratory morbidity is not entirely understood.

The aim of the present study is to assess whether body weight growth after birth is the risk factor for BPD.

Sex: All

Ages: 1 minute to 1 day old

Volunteers: No Healthy Volunteers

Inclusion criteria

• equal to or less than 32 weeks' gestational age

Exclusion criteria

• main congenital malformation
• parents' refusal

Trial design

0 participants in 2 patient groups

good body weight growth

Description:

body weight growth after birth is consistent with the growth curve

Treatment:

Other: good body weight growth

poor body weight growth

Description:

body weight growth after birth is inconsistent with the growth curve

Treatment:

Other: poor body weight growth