Bodyweight Interval Exercise in the Fed Versus Fasted State (BWE)

University of Toronto

Status

Completed

Conditions

Exercise

Treatments

Other: Fasted exercise

Other: Fed exercise

Study type

Interventional

Funder types

Other

Identifiers

NCT06240442

40799

Details and patient eligibility

About

The purpose of this study is to investigate the effects of a single session of at-home bodyweight interval exercise, performed in the fasted or fed state, on postprandial glycemic management, post-exercise fat oxidation, and overall perceptions of appetite in recreationally active females. This is a remote/online study and does not involve any visits to the laboratory.

Full description

Following the acquisition of informed consent via videoconferencing, eligibility to participate in the study will be determined using questionnaires. If inclusion criteria is met, participants will undergo virtual exercise familiarization by following a pre-recorded instructional video.

Eligible participants will be assigned, in a random order, to two metabolic trials at least 3 days apart in the follicular phase of the same menstrual cycle. These visits will be online with an investigator on videoconferencing. The two trials involve: 1) Exercise followed by breakfast; and 2) Breakfast followed by exercise.

Various outcomes will be measured throughout the metabolic trials including: blood sugar, fat oxidation and appetite. All research tools needed to acquire these methods will be delivered to participants' place of residence.

Enrollment

12 patients

Sex

Female

Ages

18 to 35 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Females 18-35 years
Recreationally active (complete <150 min of exercise 1-3 days per week) and not training for any specific sport
Experiencing monthly menstrual periods (eumenorrheic)
Are not currently on oral contraceptives, or are taking triphasic oral contraceptives
Body mass index (BMI) ≥18.5 kg/m2 and ≤30 kg/m2
Regular consumption of a breakfast meal (solid and liquid meals apply) most (≥ 4) days of the week
Have a device compatible for use with study applications (e.g., smart phone)

Exclusion criteria

Inability to safely perform physical activity as determined by the Get Active Questionnaire
Not willing to consume the standardized test drink before and after exercise
Sensitive to meal timing around exercise (e.g., gastrointestinal issues if exercise performed 10 min after the start of meal consumption or if a meal is consumed 5 min after exercise)
Inability to adhere to pre-trial protocol guidelines (e.g., caffeine or alcohol restrictions)
Physical limitations for bodyweight exercise
Are on monophasic or biphasic oral contraceptives
Regular tobacco or cannabis use (e.g., recreational and/or medical cannabis, cigarettes, e-cigarettes, vape pens, JUUL)
Regular use of drugs that may alter metabolism (e.g., corticosteroids, nSAIDs)
Diagnosed medical condition under the care of care of a physician (e.g., type 2 diabetes, cardiovascular disease) Currently enrolled in a course with Dr. Gillen