Bone Augmentation Techniques in the Mandible Posterior Region

Universidad de Especialidades Espiritu Santo

Status: Not yet enrolling

Conditions: Bone Substitutes; Alveolar Bone Grafting

Treatments: Procedure: Tridimensional Onlay allogenic bone graft; Procedure: Tridimensional Onlay xenogeneic bone graft; Procedure: Tridimensional Onlay autologous bone graft

Study type: Interventional

Funder types: Other

Identifiers

NCT06661447

2024-ODONT-002

Details and patient eligibility

About

This study aims to compare the efficacy of two bone augmentation techniques in the posterior mandible. Twenty participants will undergo 40 surgical procedures at Espíritu Santo University (UEES) in Samborondon, Ecuador. Each patient will receive two types of bone grafts: one side will use autogenous cortical bone plates with a 50/50 mixture of autogenous bone and biomaterial (as described by Dr. Fouad Khoury), while the other side will use xenogenous cortical bone plates with the same mixture.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 64 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with Bilateral Mandibular Posterior Edentulous with atrophy in 4, 5 or 6 Cawood and Howell stages.
• Patients who have good plaque control of less than 20%
• Patients between 18-64 years old

Exclusion criteria

• Systemically compromised patients
• Smoker patients
• Pregnant women, breastfeeding or use of oral contraceptives
• Patients who are taking medication that may affect healing and coagulation
• Patients with periodontal disease
• Patients who have undergone chemotherapy and radiotherapy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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40 participants in 3 patient groups

Autogenous Onlay bone graft

Active Comparator group

Description:

All patients will be submitted under a Onlay bone graft Technique with autogenous block bones is perform in one of the two Bilateral Mandibular Posterior Edentulous areas. The inner space is filled with a mixture of autogenous and xenogeneic particulated bone

Treatment:

Procedure: Tridimensional Onlay autologous bone graft

Xenogeneic Onlay bone graft

Experimental group

Description:

In 20 patients, A xenogeneic onlay bone graft is positioned in the remaining mandibular posterior edentulous area. The inner space is filled with a mixture of autogenous and xenogeneic particulated bone

Treatment:

Procedure: Tridimensional Onlay xenogeneic bone graft

Allogenic Onlay bone graft

Experimental group

Description:

In 20 patients, A allogenic onlay bone graft is positioned in the remaining mandibular posterior edentulous area. The inner space is filled with a mixture of autogenous and xenogeneic particulated bone

Treatment:

Procedure: Tridimensional Onlay allogenic bone graft