Bone Healing Study

Kazan Federal University

Status: Withdrawn

Conditions: Bone Fracture

Study type: Observational

Funder types: Other

Identifiers

NCT03244969

hematoma-2017

Details and patient eligibility

About

The aim of the research is to identify structural tissue changes in the early fracture hematomas.

Full description

The fracture hematomas obtained during reconstructive bone surgery from patients with bone fractures will be examined. Histological methods and ultra-thin sections for electron microscopy will be used to identify structural tissue changes in the granulation tissue in different period of time after bone fracture. Immunohistochemical analysis will be performed to estimate the dynamic of proliferation, differentiation and cell migration during granulation and reticulofibrosis bone tissues development.

Sex: All

Ages: 18 to 84 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Patients with fractures of the upper and lower extremities
• Patients for whom the surgical bone reconstruction are indicated