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Bone Marrow Cells in Myocardial Infarction

U

University of Oulu

Status and phase

Completed
Phase 3
Phase 2

Conditions

Acute Myocardial Infarction

Treatments

Procedure: intracoronary injection of bone marrow cells

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

This study is aimed to assess the effect of bone marrow cells on arrhythmia risk variables in patients with a acute myocardial infarction.

Full description

This is a randomized, double-blinded study, where patients treated with thrombolytic therapy for acute myocardial infarction are randomized to receive bone-marrow derived stem cells or sham-infusion at the time percutaneous coronary intervention of the target vessel. The end-points are many arrhythmia risk variables, suchs as heart rate variability, T-wave alternans and many ECG variables as well as systolic and diastolic left ventricular function.

Enrollment

100 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Acute ST-elevation myocardial infarction treated with thrombolytic therapy

Exclusion criteria

  • Indication for rescue PCI, severe clinical heart failure, age <18 years

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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