Bone Metastases Database of Patients Treated Surgically for Impending or Pathologic Fracture of Long Bones (BMD)

Istituto Ortopedico Rizzoli

Status: Enrolling

Conditions: Neoplasm Metastasis

Treatments: Procedure: intramedullary fixation or endoprosthetic reconstruction

Study type: Observational

Funder types: Other

Identifiers

NCT03416959

0012807

Details and patient eligibility

About

The aims of this study are to collect prospective data on the natural history of bone metastases (BMs) and skeleta related events (SREs),

Full description

The aims of this study are to evaluate clinical and biological factors of patients with BMs after reconstruction with intramedullary fixation (IMN) or endoprosthetic reconstruction (EPR) with a specific focus on (1) the rate of complication or failure; (2) differences in complication rates by anatomic site; (3) functional results as assessed by the Musculoskeletal Tumor Society System (MSTS); (4) differences in complication rate between patients treated with INM versus EPR; and (5) differences in survival in patients with metastatic bone disease based on disease-specific, laboratory, and demographic information.

Enrollment: 120 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with long bone metastases treated surgically with intramedullary nail or endoprosthetic reconstruction

Exclusion criteria

• Patients with bone metastases of the spine