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Bone Mineral Density Changes Among Clinical Subtypes of Parkinson's Disease

T

T.C. ORDU ÜNİVERSİTESİ

Status

Unknown

Conditions

Parkinson Disease
Bone Loss

Study type

Observational

Funder types

Other

Identifiers

NCT03806517
Ordu University 1

Details and patient eligibility

About

The bone loss in Parkinson's disease (PD) emerges as a non-motor symptom with motor and non-motor outcomes, such as fracture and musculoskeletal pain. Bone mineral density (BMD) is decreasing in patients with PD when compared to sex and age-matched healthy controls. The changes in BMD according to clinical subtypes of PD is unknown. The investigators are planning to compare the BMD status between the tremor dominant and postural instability and gait difficulty type of PD.

Full description

The investigators are planning to complete this study between January and February 2019. This study will be performed at Ordu University Education and Research Hospital, Neurology Department.

All patients admitted to the outpatient clinic will be evaluated in terms of inclusion criteria. The control group consisted of people who do not have any orthopedic, neurological or metabolic disorders which may affect the BMD.

Enrollment

75 estimated patients

Sex

All

Ages

40 to 85 years old

Volunteers

Accepts Healthy Volunteers

Inclusion and exclusion criteria

For TDT and PIGDT PD group

Inclusion Criteria:

Clinical diagnosis of idiopathic Parkinson's disease Age of 40-85 years

Exclusion Criteria:

Having additional orthopedic and neurological disorders Having metabolic disease, Having steroid drug use

For Control group

The similar age and sex-matched healthy individuals who have no orthopedic, metabolic and neurological disorders, and steroid use will be included in the study.

Trial design

75 participants in 3 patient groups

Tremor dominant type group
Description:
Tremor dominant type (TDT) group will consist of the patients with tremor premotor symptoms.
PIGD dominant type group
Description:
Postural instability and gait difficulty dominant type (PIGDT) group will consist of the patients with axial premotor symptoms.
Healthy control group
Description:
Healthy control group will consist of the subjects with same age and sex matched individuals in PD group.

Trial contacts and locations

1

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Central trial contact

Sevim ACARÖZ CANDAN, PhD

Data sourced from clinicaltrials.gov

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