Bone Status on Patients With Genetic Hemochromatosis: a 3 Years Descriptive and Evolutionary Study (FEROS)

Rennes University Hospital

Status: Completed

Conditions: Genetic Hemochromatosis

Study type: Observational

Funder types: Other

Identifiers

NCT01556360

2008-A000386-47

Details and patient eligibility

About

The purpose of this study is to describe bone status on patients with genetic hemochromatosis, at diagnostic time and his evolution under treatment.

Full description

Bone diseases have been recognized recently as complications of genetic hemochromatosis. Further studies are needed to describe the role of iron in bone injuries. The purpose of this study is to describe bone status on patients with genetical hemochromatosis, at diagnostic time and his evolution under treatment.

Enrollment: 100 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients between 18 and 80 years
• C282 homozygosity

Exclusion criteria

• corticosteroids during the last 3 months
• following treatments during the last 6 months : anabolic steroids, growth hormone, hormone therapy for menopause, tibolone, raloxifene.
• following treatments during inclusion or in the last 6 month : teriparatide, parathormone, fluor, strontium ranelate, biphosphonate.
• cancer or evolutionary hemopathy (including monoclonal gammopathy)
• pregnancy at inclusion time
• treated osteoporosis
• patient in wich follow up seems hard
• inclusion in another study incompatible with this one