Bone Structure and Strength Evaluated by Extreme-CT Scan Before and After Treatment of Hyper- and Hypothyroidism

Steen Bonnema

Status: Completed

Conditions: Hyperthyroidism; Hypothyroidism

Study type: Observational

Funder types: Other

Identifiers

NCT02005250

Thyroid Xtreme

Details and patient eligibility

About

The aim to evaluate the bone structure by Dexa-scan, extreme CT and bone markers before and one year after treatment for a thyroid functional disorder

Full description

The aim to evaluate the bone structure by Dexa-scan, extreme CT and bone markers before and one year after treatment for a thyroid functional disorder. Women with hyper- og hypothyroidism are included and undergo usual treatment. Patients are stratified into 10 different groups.

Enrollment: 93 patients

Sex: Female

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

informed consent, female sex, age 20-85 years, indication for treatment of the thyroid disorder,

Exclusion criteria

pregnancy, renal insufficiency, known osteoporosis, other disease that may affect bone metabolism, medication which affects bone metabolism, T-score below -3.5, thyroidea ophthalmopathy with indication for steroids,

Trial design

93 participants in 2 patient groups

hyperthyroidism

Description:

61 pre- and postmenopausal women with hyperthyroidism

hypothyroidism

Description:

32 pre- and postmenopausal women with hypothyroidism