BOO and DU and Their Clinical and Urodynamic Findings in Women With ≥Stage II Cystocele

National Taiwan University

Status: Completed

Conditions: Bladder Outlet Obstruction and Detrusor Underactivity in Women With Severe Cystocele

Treatments: Diagnostic Test: Pad test

Study type: Observational

Funder types: Other

Identifiers

NCT03613324

201805025RINB

Details and patient eligibility

About

Prevalence rates of bladder outlet obstruction (BOO) and detrusor underactivity (DU) and their related clinical and urodynamic findings in women with ≥ pelvic organ prolapse quantification stage II cystocele are important for clinical consultation. Thus, the aim of this study was to elucidate the above findings and between-group associations.

Full description

Between November 2011 and January 2017, medical records of all women with ≥stage II cystocele who underwent 20 min pad testing and urodynamic studies in a medical center were reviewed. Only those with complete data of maximum flow rate (Qmax) and detrusor pressure at maximum flow rate (PdetQmax) were enrolled. ANOVA test and post-hoc testing with bonferroni's correction were used for statistical analysis. Woman were defined as having DU when Qmax was <12 mL/s and PdetQmax was <10 cmH2O, and were defined as having BOO when Qmax was <12 mL/s and PdetQmax was ≥25 cmH2O with sustained detrusor contraction during voiding cystometry.

Enrollment: 455 patients

Sex: Female

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age > 20y/o
2. Cystocele > stage II
3. Complete pad test and urodynamic study

Exclusion criteria

1. Pregnancy
2. Urinary tract infection
3. Had received pelvic reconstruction surgery

Trial design

455 participants in 3 patient groups

Bladder outlet obstruction (BOO)

Description:

Between November 2011 and January 2017, medical records of all women with ≥stage II cystocele who underwent 20 min pad testing and urodynamic studies in a medical center were reviewed. Woman were defined as having BOO when Qmax was \<12 mL/s and PdetQmax was ≥25 cmH2O with sustained detrusor contraction during voiding cystometry.

Treatment:

Diagnostic Test: Pad test

Detrusor underactivity (DU)

Description:

Between November 2011 and January 2017, medical records of all women with ≥stage II cystocele who underwent 20 min pad testing and urodynamic studies in a medical center were reviewed. Woman were defined as having DU when Qmax was \<12 mL/s and PdetQmax was \<10 cmH2O during voiding cystometry.

Treatment:

Diagnostic Test: Pad test

ND BOO/DU

Description:

Between November 2011 and January 2017, medical records of all women with ≥stage II cystocele who underwent 20 min pad testing and urodynamic studies in a medical center were reviewed. This group revealed no demonstrated bladder outlet obstruction nor detrusor underactivity.

Treatment:

Diagnostic Test: Pad test