Boswellia Serrata Extract in Acute Diarrhea

Azienda di Servizi alla Persona di Pavia

Status: Completed

Conditions: Acute Diarrhea; Boswellia Serrata

Treatments: Dietary Supplement: lecithin-based delivery form of Boswellia serrata; Combination Product: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT05345028

4806/11012022

Details and patient eligibility

About

Acute diarrhea is a frequent problem worldwide, mostly due to gastrointestinal infections or food poisoning. Boswellia serrata could be active in the treatment of acute diarrhea due to its an-ti-inflammatory, antispasmodic and antimicrobial activity.

Enrollment: 49 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• presence of acute diarrhea of mild to moderate severity

Exclusion criteria

• patients with long term diarrhea
• iatrogenic diarrhea
• symptoms of functional gut disease or severe inter-current diseases
• severe diarrhea and dehydration requiring hospitalization and intravenous treatment
• subjects with high temperature (> 38.5° C)
• subjects treated by other anti-diarrheal and antibiotic drugs in the last 24 hours
• severely malnourished subjects
• pregnant women

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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49 participants in 2 patient groups, including a placebo group

Boswellia Phytosome

Active Comparator group

Treatment:

Dietary Supplement: lecithin-based delivery form of Boswellia serrata

Placebo

Placebo Comparator group

Treatment:

Combination Product: Placebo