Bowel Dysfunction and HoLEP Outcomes

Northwestern University

Status: Enrolling

Conditions: Urologic Injuries

Treatments: Procedure: Bowel function post Holmium Laser Enucleation of the Prostate

Study type: Observational

Funder types: Other

Identifiers

NCT06688500

STU00220105

Details and patient eligibility

About

The objective of this prospective study is to examine the correlation and effects of bowel dysfunction on outcomes for patients undergoing holmium laser enucleation of prostate (HoLEP) for lower urinary tract symptoms secondary to benign prostatic hyperplasia (BPH).The investigator hypothesizes that patients who have more bowel dysfunction based on higher severity scores on patient-reported validated questionnaires will experience more symptoms in the immediate post-operative period and may have slower recovery of urinary control. Assessment of pre, peri, and post-procedural bowel dysfunction via the Constipation Severity Score (CSS) and Vaizey Incontinence Questionnaire will aid the analysis.

Enrollment: 126 estimated patients

Sex: Male

Ages: 18 to 89 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Males18-89 undergoing HoLEP
• Able to read, understand, and complete patient questionnaires
• Willing to sign the informed consent form

Exclusion criteria

• Patients with bowel diversion (colostomy, ileostomy)
• Patients with known neurogenic bowel
• Patients having concurrent ureteroscopy+/-laser lithotripsy, percutaneous nephrolithotomy, or non-urologic surgery at time of HoLEP
• Anticipated need for perineal urethrostomy at time of HoLEP
• Prior pelvic radiation or patients with history of bladder cancer with or without Bacillus Calmette-Guerin (BCG) therapy
• Patients who lack decisional capacity