Brachial Artery Peak Velocity Variation to Predict Fluid Responsiveness

Hospital del SAS de Jerez

Status: Completed

Conditions: Hypotension; Shock

Treatments: Other: Fluid administration

Study type: Observational

Funder types: Other

Identifiers

NCT00890071

UIE-SCCU-200902

Details and patient eligibility

About

The investigators designed this study to determine the predictive value for predicting fluid responsiveness of noninvasive evaluation of respiratory variation of peak velocity in brachial artery, in mechanically ventilated patients with acute circulatory failure.

Full description

Predicting the hemodynamic response to fluid administration (or fluid responsiveness) in critical ill patients is still a matter of concern, since fluid overload could worse the clinical situation of these patients. Parameters of fluid responsiveness usually require an invasive monitoring (like arterial pulse pressure variation).

We hypothesize that noninvasive evaluation of respiratory variation of peak velocity in brachial artery using Doppler ultrasound could provide a feasible estimation on fluid responsiveness in mechanically ventilated patients with acute circulatory failure.

Enrollment: 38 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with controlled mechanical ventilation, equipped with an indwelling radial artery catheter and for whom the decision to give fluids will be taken because the presence of one or more clinical signs of acute circulatory failure:

  • systolic blood pressure <90 mmHg (or a decrease >50 mmHg in previously hypertensive patients)
  • the need of vasopressor drugs
  • oliguria (urine output <0.5 ml/kg/min for at least 2 h)
  • tachycardia
  • delayed capillary refilling
  • the presence of skin mottling

Exclusion criteria

• Contraindication for the volume administration: evidence of fluid overload and/or of hydrostatic pulmonary edema
• Patients with instable cardiac rhythm

Trial design

38 participants in 1 patient group

Acute circulatory failure

Description:

Patients for whom the decision to give fluids was taken because the presence of one or more clinical signs of acute circulatory failure.

Treatment:

Other: Fluid administration