ClinicalTrials.Veeva

Menu

Brain and Cognitive Reserve (BCN)

Civil Hospices of Lyon logo

Civil Hospices of Lyon

Status

Completed

Conditions

Brain Ischemia

Treatments

Other: neurologic and neuropsychological evaluation

Study type

Interventional

Funder types

Other

Identifiers

NCT02819167
69HCL16_0151

Details and patient eligibility

About

Ischemic strokes are one of the leading causes of handicap and death in elderly people in France.

Cognitive reserve (CR) is an active model, defined as a function of lifetime intellectual activities and other environmental factors that explain differential susceptibility to functional impairment in the presence of pathology or other neurological insult. CR is estimated using variables for cognitive activity: years of education, professional status, socioeconomic status... Furthermore, brain reverse (BR) is a passive and quantitative model that depend on brain size and other quantitative aspects of the brain that explain differential susceptibility to functional impairment in the presence of pathology.

Firstly, volume and localization of ischemic strokes have a great impact on CR and BR due to brain injury. On the other hand, CR influences the severity and the expression of cognitive diseases.

The investigators realize a prospective study in order to assess the impact of CR and BR on cognitive prognosis after a right middle cerebral artery ischemic stroke in elderly patients.

Enrollment

20 patients

Sex

All

Ages

70+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • ≥70 years old
  • right middle cerebral artery ischemic stroke
  • hospitalized in neurovascular unit of Pierre Wertheimer hospital between January 2015 to January 2016

Exclusion criteria

  • Contraindication for MRI
  • Hemorrhagic stroke
  • Aphasia

Trial design

Primary purpose

Basic Science

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

20 participants in 1 patient group

neurologic and neuropsychological evaluation
Other group
Treatment:
Other: neurologic and neuropsychological evaluation

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2025 Veeva Systems