Brain Diseases on 7.0T Magnetic Resonance Imaging

Chinese PLA General Hospital (301 Hospital)

Status: Enrolling

Conditions: MRI; Brain Tumor; Cerebrovascular Disease

Treatments: Diagnostic Test: Magnetic resonance imaging

Study type: Interventional

Funder types: Other

Identifiers

NCT05287750

Brain Diseases-ChinaPLAGH

Details and patient eligibility

About

This clinical trial studies the use of 7-Tesla (7T)and 3T magnetic resonance imaging (MRI) in detecting brain diseases. 7T MRI has increased detection sensitivity, including more accurate lesion delineation, higher inter-rater agreement. Diagnostic procedures such as 7T MRI may help ultimately improved diagnostic and therapies confidence to inform decision making than standard 3T MRI.

Full description

7T MRI increased detection sensitivity, attain superior anatomic resolution, higher spatial and spectral specificity of advanced quantitative techniques, and shorter scan times than 3T MRI. When applied clinically, these benefits translate to increased detection sensitivity, and ultimately improved diagnostic and therapies confidence to inform decision making. This study aim to detect the image characteristics and diagnostic accuracy of brain diseases on 7T MRI.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age≥18 and ≤80
• Having brain diseases (eg: brain tumor, cerebrovascular diseases)
• Having no contraindications against MRI or intravenous contrast agent administration
• Clinically stable

Exclusion criteria

• Age<18 or >80
• Pregnancy and other contraindication to MRI scan
• Informed consent not obtained

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)