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Sacral neuromodulation (SNM) has become an accepted treatment for patients with refractory lower urinary tract dysfunction such as urgency frequency syndrome, urgency incontinence, non-obstructive chronic urinary retention and chronic pelvic pain syndrome. Modulation of central afferent activity is considered critical to this therapeutic effect but the neural mechanisms are poorly understood.
We hypothesize that SNM has a significant effect on brain activity detectable by positron emission tomography (PET).
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Interventional model
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30 participants in 2 patient groups
There are currently no registered sites for this trial.
Start date
Oct 01, 2005 • 19 years ago
End date
Jun 01, 2009 • 15 years ago
Today
Jan 22, 2025
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Data sourced from clinicaltrials.gov
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