Brain Exercises for Synaptic Plasticity (BEST)
Status
Conditions
Treatments
Details and patient eligibility
About
The BEST study will investigate the feasibility of cognitive interventions in a randomized, placebo-controlled, clinical trial. The investigators will recruit 45 cognitively normal subjects and engage them in one of three cohorts over an 8 week period, including active reading vs. origami study arms and a placebo group without structured cognitive intervention.
Full description
This is a randomized, placebo controlled study investigating the practical implementation and conduct of two cognitive interventions in non-demented subjects. Subjects will be randomized 1:1:1 into three groups including: 1) a Book club that includes weekly one hour meetings and daily reading assignments, 2) Origami lessons (one hour/week) with daily take home Origami activities to complete, and 3) a placebo group with unstructured lifestyle activities (normal lifestyle activities without restraint).
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Non demented community dwelling elders
Exclusion criteria
- Unable to perform the reading or origami tasks for any reason
Trial design
Primary purpose
Allocation
Interventional model
Masking
45 participants in 3 patient groups, including a placebo group
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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