Brain Function and Psychological Changes Related to Cell Therapy for Autoimmune Hemolytic Anemia

Institute of Hematology & Blood Diseases Hospital, China

Status

Enrolling

Conditions

Psychological Well-Being

Brain Function

Autoimmune Hemolytic Anemia

CAR T-cell Therapy

Treatments

Other: Brain function and psychological assessment

Study type

Observational

Funder types

Other

Identifiers

NCT06921980

QTJC2025011

Details and patient eligibility

About

Cell therapy is an innovative treatment with significant efficacy in hematologic and certain autoimmune diseases. Although it offers potential benefits for autoimmune hemolytic anemia (AIHA), it may result in cognitive and other potential impairments, which can adversely affect patients' cognition and behavior.

Brain function and psychological assessment are essential for the early detection of potential impairments, allowing timely interventions to prevent complications and ensure patient safety. This study aims to comprehensively evaluate the physical and psychological impacts of cell therapy on AIHA patients to develop safer and more effective treatment strategies that enhance their quality of life.

Enrollment

20 estimated patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Diagnosis of AIHA
Subjects will receive cell therapy such as CAR T-cell therapy
Male or female, aged 18-65 years
Willing and able to comply with the requirements for this study and written informed consent

Exclusion criteria

History of psychiatric illness
History of severe brain disease
Subjects that the investigator believes have other reasons that make them unsuitable for inclusion in this study