Brain Functional Connectivity Changes Following Cognitive Rehabilitation in Multiple Sclerosis: an fMRI Study

Sina Hospital, Iran

Status: Completed

Conditions: MS (Multiple Sclerosis)

Treatments: Behavioral: Cog Rehab

Study type: Interventional

Funder types: Other

Identifiers

NCT01628276

MSRC-AE-DCM-1

Details and patient eligibility

About

This trial seeks to investigate brain network changes following cognitive rehabilitation in MS patients. The investigators hypothesize that rehabilitation interventions improve connectivity in the brain.Novel Magnetic Resonance Imaging technique is performed to investigate changes in brain plasticity.

Enrollment: 45 patients

Sex: All

Ages: 18 to 54 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Definitive MS diagnosis
• Right handedness
• EDSS 0-4
• No relapse in past 6 weeks
• Willing to consent and participate in the study

Exclusion criteria

• Pregnancy
• Left handedness
• Neurologic or psychiatric disorder other than MS

Trial design

45 participants in 3 patient groups

Rehab first

Experimental group

Treatment:

Behavioral: Cog Rehab

Rehab Second

Experimental group

Treatment:

Behavioral: Cog Rehab

Non Rehab

No Intervention group