Brain Health in Midlife (ADORE BRAIN)

University of Kansas

Status: Completed

Conditions: Pre-Eclampsia; Alzheimer Disease; Gestational Hypertension; Pregnancy Related; Cardiovascular Diseases; Brain Health; Dementia

Treatments: Diagnostic Test: A combination of various test and biomarkers will be completed to understand the effect of hypertensive disorders of pregnancy in brain health in midlife.

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT06640842

STUDY00160885

P30AG072973 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The purpose of this study is to learn if hypertensive disorders during pregnancy affects brain health in midlife.

Enrollment: 24 patients

Sex: Female

Ages: 18 to 54 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Participated in the ADORE trial ( R01 HD083292)

Exclusion criteria

• History of seizures or Epilepsy
• Pregnant at screening
• Ineligible to complete MRI due to metal in the body

Trial design

24 participants in 2 patient groups

Hypertensive disorder of pregnancy

Description:

Women who were diagnosed with a hypertensive disorder of pregnancy during the ADORE study participation.

Treatment:

Diagnostic Test: A combination of various test and biomarkers will be completed to understand the effect of hypertensive disorders of pregnancy in brain health in midlife.

Healthy pregnancy

Description:

Women who participated in the ADORE study and had a healthy pregnancy during their participation.

Treatment:

Diagnostic Test: A combination of various test and biomarkers will be completed to understand the effect of hypertensive disorders of pregnancy in brain health in midlife.