Brain Hippocampal Volume Relationship With Anxious Symptoms in Major Depressive Patients

Hospital Universitario Dr. Jose E. Gonzalez

Status

Unknown

Conditions

Major Depressive Disorder

Anxiety Disorders

Treatments

Drug: Sertraline

Study type

Interventional

Funder types

Other

Identifiers

PS18-00016

Details and patient eligibility

About

The objective of this transversal study is to determine if there is a difference in the volume of the hippocampus with the degree of anxiety.

Enrollment

30 estimated patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

First-time patients, without prior antidepressant treatment that meet the diagnostic criteria of DSM 5 for major depressive disorder.
Patients who meet the current major depressive disorder criteria in the MINI interview.
Patients who signed the informed consent for the investigation.

Exclusion criteria

Patients presenting insufficient data in the MINI interview for current major depression.
Patients diagnosed with intellectual development disorder, by clinic.
Patients with diagnosis of the schizophrenic spectrum, bipolar disorder, autism spectrum disorder, post-traumatic stress disorder and obsessive-compulsive disorder by clinic and / or by the MINI interview.
Patients with contraindications for MRI.
Patients with serious or unstable medical problems.
Patients undergoing some legal procedure.
Patients with difficulties in understanding the interview or completing the assessment instruments.