Brain Metabolic Network of PET in Patients With Advanced Non-Small Cell Lung Cancer

Fifth Affiliated Hospital, Sun Yat-Sen University

Status: Completed

Conditions: Advanced Non-small-cell Lung Cancer

Treatments: Other: None of any intervention

Study type: Observational

Funder types: Other

Identifiers

NCT05380908

K059(2021-059)

Details and patient eligibility

About

This study is a retrospective study, screening patients with systemic PET / CT scan in our department, enrolling the ones who meet the criteria, collect their information and resting state brain PET images.Then make the brain metabolic network analysis and statistical analysis to explore the PET brain metabolic network of non-small cell lung cancer patients and the effect of chemotherapy drugs on brain metabolic network in patients with advanced lung cancer.

Full description

1. Enroll Participants
2. Collect PET/CT Images
3. Images Analysis
4. Statistical Analysis

Enrollment: 90 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with advanced non-small cell lung cancer without any treatment and pathological confirmed non-small cell lung cancer.

Exclusion criteria

• Brain tumors (primary or metastasis), previous surgery, radiotherapy, chemotherapy, stroke, head trauma, psychiatric history (insomnia, depression, mania, schizophrenia and other psychiatric disorders), or history of drug dependence (e. g. sedatives, sleeping pills or sedatives)

Trial design

90 participants in 3 patient groups

Patients with untreated non-small cell lung cancer

Treatment:

Other: None of any intervention

Patients with non-small cell lung cancer after chemotherapy

Normal controls

Treatment:

Other: None of any intervention