Brain Natriuretic Peptide (BNP) Usefulness In Elderly Dyspneic Patients (BED)

Assistance Publique - Hôpitaux de Paris

Status: Completed

Conditions: Heart Failure

Study type: Observational

Funder types: Other

Identifiers

NCT00658216

SCR 06 007

Details and patient eligibility

About

The purpose of this study is to test the usefulness of measuring plasma brain natriuretic peptide (BNP) for diagnosis and prognosis in very elderly dyspneic patients.

Full description

Measurement of BNP concentration is approved for use in the diagnosis of heart failure (HF) in elderly patients below 80 years of age. The value of plasma BNP assays as diagnostic tools has not been determined in very elderly populations because the plasma BNP increases with age. This large, multicenter, prospective, observational, study in 300 participants is aimed to prospectively test the usefulness of measuring plasma BNP for diagnosis of HF in dyspneic patients aged 80 and older.

Enrollment: 390 patients

Sex: All

Ages: 80+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• acute dyspnea
• crackles on lung auscultation,
• hypoxemia,
• right-sided signs.

Exclusion criteria

• no exclusion criteria

Trial design

390 participants in 1 patient group

Longitudinal

Description:

Prospective study : cohort of consecutive patients recruited over 2 years