Brain Oxygenation During Prehospital Anesthesia: an Observational Study (BOPRA)

Helsinki University Central Hospital (HUCH)

Status

Active, not recruiting

Conditions

Emergencies

Major Trauma

Critically Ill

Anesthesia

Treatments

Diagnostic Test: Cerebral near-infrared spectroscopy

Study type

Observational

Funder types

Other

Identifiers

NCT04144803

BOPRA

Details and patient eligibility

About

Brain oxygenation of adult patients undergoing prehospital emergency anesthesia is monitored using noninvasive near-infrared spectroscopy. Patients are afterwards interviewed to define neurological outcome to measure quality of life. The purpose of this study is to reveal the risk factors of prehospital anesthesia related cerebral desaturation events (CDE) and to define the association between CDE and survival, neurological outcome or quality of life.

Enrollment

1,300 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

sedation or anesthesia provided to facilitate endotracheal intubation, performed by Helicopter Emergency Medical Services (HEMS) team regardless of the reason

Exclusion criteria

Ongoing cardiopulmonary resuscitation at the time of intubation
Physical barrier for near-infrared spectroscopy measuring (e.g. forehead laceration)
HEMS unit does not escort patient to the hospital (exception: in case of death on scene after inclusion, patient is included)
Workload too high to ensure standard level of clinical care during the study
For interviews: no competence in Finnish, Swedish or English