Brain Vital Signs M-Score: Point-of-care Monitoring for Motor Recovery After Stroke

HealthTech Connex

Status: Terminated

Conditions: Stroke

Treatments: Other: Recording of electroencephalographic (EEG) data

Study type: Observational

Funder types: Industry

Identifiers

NCT03858699

HTC_MScore_001

Details and patient eligibility

About

The purpose of this study is to investigate brain signals relating to motor function, using electroencephalography (EEG) technology. The aims of the study can be separated into 3 specific study objectives:

1. Record EEG data from control participants and individuals with stroke during basic motor tasks and build a database of EEG signals to enable analysis of motor control.
2. Apply signal processing algorithms to extract EEG features related to motor control.
3. Develop a framework/the motor score (M-Score) that uses the EEG signals, in combination with machine learning approaches, to quantify motor control ability.

Enrollment: 22 patients

Sex: All

Ages: 19 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age requirements:

  • Younger adult control participants (19-40 years old)
  • Older adult control participants (41-80 years old)
  • Individuals with stroke (19-80 years old)

• Capacity to follow single stage commands

• Stroke specific inclusion criteria

  • Upper-limb disability as a result of a stroke (>1 month ago)

Exclusion criteria

• Cognitive difficulties that undermine ability to give informed consent (Montreal Cognitive Assessment (MoCA) score below 23).
• Severe paralysis such that the participant cannot perform simple movements (such as finger tapping, clicking a mouse, etc.)
• History of head trauma, a major psychiatric diagnosis, neurodegenerative disorder or substance abuse

Trial design

22 participants in 2 patient groups

Individuals with stroke

Description:

Participants in sub-acute and chronic phases post-stroke (\>1 month post-stroke) will be recruited for participation in this study.

Treatment:

Other: Recording of electroencephalographic (EEG) data

Adult control participants

Description:

Even age distributions will be recruited in the adult control group, stratified under 40 years old and over 40 years old.

Treatment:

Other: Recording of electroencephalographic (EEG) data