Branched-chain Amino Acids, and Resistance Exercise on Skeletal Muscle Signaling Pathways

University of Sao Paulo

Status: Completed

Conditions: Healthy

Treatments: Dietary Supplement: BCAA supplementation; Dietary Supplement: Leucine supplementation; Dietary Supplement: Alanine supplementation

Study type: Interventional

Funder types: Other

Identifiers

NCT01350427

2011/04690-6

Details and patient eligibility

About

This study aims to evaluate the effects of leucine and branched-chain amino acids supplementation on skeletal muscle remodeling signaling pathways induced by resistance exercise.

Enrollment: 18 patients

Sex: Male

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Sedentaries
• Must be able to exercise
• Must be able to swallow tablets

Exclusion criteria

• Use of nutritional supplements
• Use of anti-inflammatory drugs

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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18 participants in 3 patient groups, including a placebo group

Leucine

Experimental group

Treatment:

Dietary Supplement: Leucine supplementation

BCAA

Experimental group

Treatment:

Dietary Supplement: BCAA supplementation

Placebo

Placebo Comparator group

Treatment:

Dietary Supplement: Alanine supplementation